Gulab Khandelwal started writing poetry at an early age. His first volume of poems was published in 1941 with preface by the famous poet Suryakant Tripathi ‘Nirala’. Since then, 73 books have been published, including more than 50 volumes of poems and 2 dramatic works in prose, some of which have been digitised by the Digital Library of India. Six of his books have received awards from the Uttar Pradesh government and one has received an award from the Bihar government. Some of his books were selected as textbooks for colleges in Uttar Pradesh and Bihar, with Alok Vritt used in the intermediate board in Uttar Pradesh, India, since 1976.

Mahakavi Gulab translated some of his poems in English in Gulab Khandelwal: Selected Poems, which was published in 1986 with preface by Dr. Karan Singh, ex-Prince of Kashmir. In recognition of this and his achievements in his literary career, he was awarded honorary citizenship of Baltimore City, USA on 13th July, 1985. Furthermore, both the mayor of the City of Baltimore and the governor of Maryland state declared this day as Hindi Day.

Mahakavi Gulab was the president of Archana, a literary society of Kolkata founded in the fifties and presided over many events organized by multiple literary organizations. He was the president of Akhil Bhartiya Hindi Sahitya Sammelan, Prayag, for 18 years. He was also the president of Bharati Parishad, an organisation founded by Mahamana Madan Mohan Malaviya. For 15 years, he was the senior member of the editorial board of Vishwa, a literary magazine by the International Hindi Association. He was also the president of the International Hindi Association.

Mahakavi Gulab lived mostly in the USA, but visited India every year. Till his death, he was active in his literary pursuit. In addition to his involvement in the Indian literary organizations, he also worked extensively with Indian organizations in the United States. He presided on meetings in New York on Vishwa Hindi Sammelan, an organization which strives towards the firm establishment of the Hindi language. At the age of 82, he wrote his auto-biography ज़िन्दगी है कोई किताब नहीं (Zindagi Hai Koi Kitaab Nahi).